this professor is making arteries with an off-the-shelf 3d printer

by:INDUSTRIAL-MAN     2019-10-18
Four years ago, when Adam Fanberg tried to figure out how to synthesize human tissue, his supply became flat: a kitchen mixer, some gelatin bags on the supermarket baking aisle, a $2,000 3D printer
\"I didn\'t have external funding at the beginning, so we did it a little cheaper,\" said Finn Berg, a 38-year-old biomedical engineer who runs a lab at Carnegie Mellon University in Pittsburgh.
In a paper published today in the journal Scientific Progress, fan Bohe and his colleagues described how they ended up improving techniques for printing copies of arteries, brain tissue structures, and other organs composed of proteins such as collagen and fiber protein.
Although the form they create is not a functional organ with active cells, one day they can be used as a scaffold to support the actual tissue.
Doctors have used 3D printing technology to support the baby\'s damaged trachea, make titanium chin replacements, and synthesize tiny liver to test potential drug therapies.
There are many obstacles to building a fully functional custom organ and preparing for implantation.
But this new study has brought hope for the future to tailor-made organizations for medical treatment, a step closer to reality.
Feinberg\'s basic advancement is to find out how to prevent the soft structure created by the modified MakerBot 3D printer from crashing under its own weight.
Unlike the normal material plastic of the 3D printer, collagen does not maintain its shape as it is when synthesized, unless it has some support.
The research team began to think about Jell-
O the mold can suspend fruit fragments in a sugary gel.
They did the experiment with gelatin and mixed it into a slurry of fine particles.
The slurry will support the structure being built layer by layer while still allowing the nozzle of the printer-
Modified with syringe-to move freely.
When the printed object is finished, it will be fixed together by itself, and the supporting gel can melt in the water at the water temperature.
The process is relatively simple, says Tommy Angelini, a professor at the University of Florida, meaning it will allow others to build on innovation, and his lab recently released a similar approach to complex tissue engineering
He was not involved in the study by Van Berg.
\"This is a very easy to get multi-functional approach,\" Angelini said . \".
Making tissue that can be implanted into the patient remains a challenge for the future.
\"This will happen in the end, but there is still a lot of basic science to do,\" Angelini said . \".
In the short term, the new method of 3D printing may allow doctors to test medical treatment on laboratory reproductions in the patient\'s body parts.
Pharmaceutical companies can use this model to test new drugs that are at greater risk before they are used in humans.
We have animal models now. mice and rats—and we have [human]
There are not many clinical trials, \"said Van Berg.
\"You can basically be a patient --
Specific parts of the heart muscles.
\"Fanberg\'s research was funded by the National Institutes of Health and the National Science Foundation.
But his initial strategy was to hack. the-
The shelf printer and the purchase of some gelatin packaging can still tell him how the lab works.
Although Carnegie Mellon University has applied for a patent to support the bath, his team is releasing information on how to modify the MakerBot printer to handle biological materials in an open environmentSource License.
He also showed up with bio-printing technology at a local school, replacing collagen with chocolate icing.
\"We think it\'s much easier to use these cheaper machines,\" said Van Berg . \".
\"We can modify it in any way we need it.
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